Adalimumab-associated bullous pemphigoid in a patient with ulcerative colitis
نویسندگان
چکیده
BP: bullous pemphigoid TNF: tumor necrosis factor INTRODUCTION Bullous pemphigoid (BP) is an uncommon skin condition in which erythematous, urticarial papules and plaques progress to form tense bullae, typically in elderly men and women. In this disease, IgG autoantibodies are directed against hemidesmosome proteins, resulting in the formation of subepidermal vesicles. At least 50 drugs have been associated with BP, including the antietumor necrosis factor (TNF)-a drugs etanercept, infliximab, and adalimumab. Here we describe a case of suspected adalimumabinduced BP in a patient with ulcerative colitis.
منابع مشابه
Bullous Pemphigoid with Lymphocytic Colitis: A Case Report and Short Literature Review
The association of autoimmune bullous diseases (i.e., bullous pemphigoid, linear IgA disease, mucous membrane pemphigoid and IgA pemphigus) and inflammatory bowel disease, namely ulcerative colitis and Crohn's disease has formerly been reported. However, to our knowledge, we report herein the first case of lymphocytic colitis with concomitant bullous pemphigoid.
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